Contamination of pharmaceutical fluids, especially injectable fluids, with bacteria is of great concern in the health care field. Sepsis due to contaminated intravenous fluids or injectable fluids has resulted in deaths. Monitoring for bacterial contamination in these fluids is especially difficult due to the low levels of contamination that are of concern. The InnovaPrep liquid-to-liquid concentrator coupled with a sensitive detection method can provide the ability to detect bacterial contamination at these low levels.